Because the oral cavity surfaces
are in close proximity with the surfaces of the trachea and lower airway,
bacteria that reside in the oral cavity can be breathed into the lower airway,
causing infection. These bacteria may be pathogenic bacteria which are not
normal members of the oral flora or they may be opportunistic organisms.
Additionally, oral inflammation, for example, in the form of gum disease, can
result in the release of biologically active inflammatory mediators into the
oral fluids that may also be breathed into the airway and cause inflammation
and increased susceptibility to infection.
Recent
evidence suggests that oral bacteria and oral inflammation can be associated
with respiratory diseases and conditions that can cause serious illness and
even death. Furthermore, some respiratory illnesses, such as asthma, may
have an effect on oral facial morphology or even on dentition. There are
several important respiratory diseases that may be influenced by oral bacteria
or oral inflammation.
§ Pneumonia
- Pneumonia is an infection of the lungs that is caused by bacteria,
mycoplasma, viruses, fungi, or parasites. Bacterial pneumonia is a common
and significant cause of death and illness in the human populations.
Pneumonia, together with influenza, is an important cause of throughout
the world. Pneumonia also contributes to morbidity and a decline in the
quality of life as well as increased medical costs. Bacterial pneumonia
is composed of several subtypes, all of which have a correlation to oral health
status.
§ Chronic
Obstructive Pulmonary Disease (COPD) - Patients with COPD have chronic airflow
obstruction due to narrowing of the airways, with excess production of sputum
resulting from chronic bronchitis and/or emphysema. Chronic bronchitis is
defined as the result of irritation to the bronchial airway and excessive
secretion of mucus sufficient to cause cough with expectoration for at least
three months of the year over two consecutive years. Emphysema results
from the distention of the air spaces next to the terminal bronchiole with
destruction of the alveolar septa. Although this condition is associated
with certain symptoms, the definitive diagnosis of emphysema can only be made
by observation on a tissue level.
Recent
research points to possible associations between oral health, especially dental
plaque and gum disease, and respiratory diseases such as community-acquired
pneumonia and COPD. Further research into these associations may allow development
and routine implementation of simple and effective strategies to prevent
respiratory disease in vulnerable populations.
photo
credit: nlm.nih.gov
article
source: Scannapieco, Frank & Mylotte, Joseph; Periodontal
Disease and Overall Health: A Clinician's Guide
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